Though you'll try to understand the direction your friend wants to take and to support them in their choices, you'll both find that your paths conflict. Your instincts will tell each of you to do things very differently. Your beliefs will be far apart and you won't see eye to eye on the right way to do things.
Or, you might find yourselves holding back on your own path in order to continue the friendship. An influence like this could hurt an otherwise good relationship. Making compromises will be necessary, but not at the expense anything else important. If you find that you're straying too far off-course from pursuing your goals, it might be time to face the fact that there are some crossed signals between you. Accepting your differences and getting on your own track will be the best, but possibly the hardest, way to handle things.