You'll each notice subtle differences in the ways that your minds work. You'll process things intellectually in different ways, first off; you're more analytical about life than your friend, and you'll be confused by their more emotional way of dealing with changes. They, on the other hand, will have a hard time understanding how analysis and thinking things through could matter at a time of intense emotion.
Neither one of you will be right or wrong. You'll basically suffer a conflict of the mind versus the emotions. It'll just be two different ways of dealing with things, which could be hard to get in sync. In this particular way, you'll be speaking two different languages. You can make the effort to talk about your individual needs, listen to each other and really try to form your responses to each other according to what your pal needs -- not what is your instinct to give.